Tumour Angiogenesis and p53 Protein Expression in Mammary Phyllodes Tumors
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چکیده
منابع مشابه
Hspb1 and Tp53 Mutation and Expression Analysis in Cat Mammary Tumors
Background: Molecular marker based cancer diagnosis gaining more attention in the current genomics era. So, Hspb1 and Tp53 gene characterization and their mRNA expression might be helpful in diagnosis andprognosis ofcat mammary adenocarcinoma. It will also add informationin comparative cancer genetics and genomics. Objectives: Eight tumors of Siamese cats were analyzed to ascertain germ-line an...
متن کاملStromal nitric oxide synthase (NOS) expression correlates with the grade of mammary phyllodes tumour.
BACKGROUND Nitric oxide synthase (NOS), particularly endothelial and inducible forms (e/i-NOS), are expressed in various cancers, including breast cancer. In mammary fibroepithelial lesions, NOS expression in stromal cells has been reported to be lower in fibroadenomas than in phyllodes tumours. AIMS To investigate NOS expression in phyllodes tumours of varying degrees of malignancy. METHOD...
متن کاملAn approach to malignant mammary phyllodes tumors detection.
BACKGROUND/AIM Mammary phyllodes tumors (MPT) are uncommon fibroepithelial (biphasic) neoplasms whose clinical behavior is difficult to predict on the basis of histological criteria only. They are divided into benign, borderline malignant and malignant groups. Sometimes it appears difficult to distinguish these tumors from other types of soft tissue sarcomas. Because of the relatively scant dat...
متن کاملStromal CD10 expression in mammary fibroadenomas and phyllodes tumours.
BACKGROUND/AIMS CD10 (CALLA) has recently been reported to be expressed in spindle cell neoplasia, and has been used to differentiate endometrial stromal sarcoma from leiomyoma and leiomyosarcoma. In the breast, myoepithelial cells express CD10, but there are few studies of the expression of CD10 in mammary fibroepithelial lesions. METHODS Stromal CD10 expression was studied in 181 mammary ph...
متن کاملPatterns of p53 expression in phyllodes tumors of the breast--an immunohistochemical study.
Authors performed an immunohistochemical analysis using monoclonal antibody to p53 protein on 15 cases of benign and malignant phyllodes tumor of the breast along with a review of other conventional clinicopathological parameters to investigate the meaning of p53 expression. The cases were composed of 8 benign and 7 malignant lesions. The pattern of p53 expression showed a statistically signifi...
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ژورنال
عنوان ژورنال: Modern Pathology
سال: 2003
ISSN: 0893-3952,1530-0285
DOI: 10.1097/01.mp.0000089907.67419.42